The Annunciation with Saint Margaret and Saint Ansanus is a painting by the Italian Gothic artists Simone Martini and Lippo Memmi, now housed in the Uffizi Gallery in Florence, Italy. It is a wooden triptych painted in tempera and gold, with a central panel having double size. Considered Martini's masterwork and one of the most outstanding works of Gothic painting, the work was originally painted for a side altar in Siena Cathedral. Simone Martini, 1333 — painted at 49. Panel and tempera. 265 × 305 cm. In the Uffizi Gallery. International Gothic and Gothic painting. Wiki link