@ Colts W 48–27
Monday, December 22, 2025
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8:15 PM – 11:30 PM
Lucas Oil Stadium, Indianapolis, IN
San Francisco 49ers @ Indianapolis Colts Week 16 Lucas Oil Stadium, Indianapolis, IN TV: ESPN Final: SF 48, IND 27 https://www.espn.com/nfl/game/_/gameId/401772824/49ers-colts
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